ncRNA name | hsa-miR-99a |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell lines SO-RB50 and Y79 |
Methods | CCK-8 assay, colony formation assay, apoptosis assay, transwell assay, transfection, qRT-PCR, Western blot |
Expression pattern | up-regulated |
Functional description | The anti-tumor activities of curcumin on Rb cells appeared to be via up-regulation of miR-99a, and thereby inhibition of JAK/STAT pathway. |
PubMed ID | 30526546 |
Year | 2018 |
Title | Curcumin inhibits proliferation, migration, invasion and promotes apoptosis of retinoblastoma cell lines through modulation of miR-99a and JAK/STAT pathway. |
Drug-related ncRNA | YES (curcumin) |
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